On 8 June 2023, the European Commission published an amendment of Annex XVII to the Regulation (EC) 1907/2006 (REACH) regarding substances recently classified as Carcinogenic, Mutagenic, or Reproductive toxicant (CMR) by the 18^th Adaptation to Technical and Scientific Progress of the Regulation (EC) 1272/2008 (CLP).

The newly classified CMR substances of categories 1A and 1B as established by Commission Delegated Regulation (EU) 2022/692, are listed in Appendix 2 and 6 (entries 28 and 30) to Annex XVII to REACH Regulation.

Ingredients used in cosmetics which are now classified as CMR (prohibited) are the following:

• Benzophenone (CAS 119-61-9) – Carcinogenic 1B
• Teophylline (CAS 58-55-9) – Reprotoxic 1B
• Pentetic Acid (CAS 67-43-6) – Reprotoxic 1B
• Pentasodium Pentetate (CAS 140-01-2) – Reprotoxic 1B

The Commission Regulation shall apply from 1 December 2023.

References:

Commission Regulation (EU) 2023/1132 of 8 June 2023 amending Regulation (EC) No 1907/2006 of the European Parliament and of the Council as regards carcinogenic, mutagenic or reproductive toxicant substances subject to restrictions.