The International Fragrance Association (IFRA), founded in 1973, represents the interests and is the voice of the fragrance industry worldwide. It promotes the safety and benefits of the fragrance industry’s products through stakeholder dialogue on a global basis.
IFRA is preparing the 51st Amendment to its standards. This amendment includes a revision of the standards format, of the guidance for their use, and of the annex on contributions from other sources. It also includes the following new and revised standards:
- 34 new IFRA Restriction Standards to control potential dermal sensitization effects for which the systemic toxicity endpoints have also been evaluated (like Isobutyl cinnamate, cis-3-Nonenyl acetate and Ethyl and methyl furaneol).
- 11 new IFRA Restriction Standards to control potential dermal sensitization effects based solely on QRA2 (including carvyl acetate, methyl lavender ketone and 3-Octen-2-one).
- 2 new IFRA Restriction Standards, for which Risk Management is based on, Threshold of Toxicological Concern (TTC) for Methoxycyclododecane and 7-Methoxy-3,7-dimethyloct-1-ene.
- 1 new IFRA Restriction Standard due to potential of depigmentation for Cresols.
- 1 new IFRA Prohibition Standard due to potential genotoxicity effects for 3-Acetyl-2,5-dimethylfuran.
- 8 Revised IFRA Restriction Standards to control potential dermal sensitization effects for which the systemic toxicity endpoints have been evaluated (including carvone, eugenol, and hydroxycitronellal).
- 1 Revised Restriction Standard based on new dermal sensitization data for 3-Propylidenephthalide.
- 1 Revised Restriction Standard based on phototoxicity and systemic toxicity for Methyl-N-methylanthranilate.
- 1 Revised Restriction Standard for Farnesol.
The proposed amendment is open for consultation until February 28, 2023, in order to give the industry the opportunity to submit its comments.
Official notification of the 51st Amendment is expected in June 2023.
1. IFRA Standards – IFRA launches consultation on update to safe use program.